AMPK is necessary for Treg functional adaptation to microenvironmental stress during malignancy and viral pneumonia
DNA methylation · mouse · 53 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Mus musculus (mouse)
- Samples
- 53 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- AMPK is necessary for Treg functional adaptation to microenvironmental stress during malignancy and viral pneumoniaThe Journal of clinical investigation · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE249019_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA1047015 and SRA study SRP475140. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 53 more — browse all 53 samples with per-sample file links →
- GSE249017 AMPK is necessary for Treg functional adaptation to microenvironmental stress during malignancy and viral pneumonia 41 samples shares ampk, microenvironmental, adaptation, malignancy, necessary, pneumonia, stress, viral
- GSE266874 Pan AMPK-activator O304 ameliorates oxidative stress in MASLD, reverses lipid zonation and reveal lobular metabolic heterogeneitites in the murine live 30 samples shares ampk, stress
- GSE293841 Rps15 mutation drives B cell malignancy through translational rewiring, oxidative stress and genomic instability 51 samples shares malignancy, stress
- GSE305462 Rac1 palmitoylation is required for cardiac stress adaptation and regulation of Protein Kinase A signaling 18 samples shares adaptation, stress
- GSE315845 Primary Cilia Mediate Stress Vulnerability and Exercise Antidepressant Adaptation: Evidence for Ventral Hippocampal Astrocytic Ciliary Remodeling by Exercise 9 samples shares adaptation, stress
- GSE290022 Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827 64 samples shares ampk
- GSE270826 AMPK promotes TFEB transcriptional activity through dephosphorylation at both mTORC1-dependent and -independent sites 48 samples shares ampk
- GSE335135 CD36 gates nocturnal hypertension by regulating inactive period blood pressure variation via renal AMPK/HDAC5/PER1 axis 37 samples shares ampk
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.