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Mapping the female mouse chromatin accessibility landscape by UUATAC-seq

GSE249077 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 23 samples 2025/07/14 GPL28330
Summary
The current understanding of regulatory sequences in the vertebrate genome is still incomplete. By introducing an adapter switching strategy, we developed an ultra-throughput ultra-sensitivity single-nucleus ATAC-seq (UUATAC-seq) protocol that enables construction of high-quality chromatin accessibility landscape from one species in a one-day experiment. By using UUATAC-seq, we mapped open chromatin regions for five representative vertebrate species at the landscape scale.
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