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LFA-1 regulated by IL-2/STAT5 pathway boosts antitumor function of intratumoral CD8+ T cells for improving anti-PD-1 antibody therapy

GSE249184 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/05/01 Platform GPL28330
Summary
These findings indicate that LFA-1-midiated immune synapse acts as a regulator of the antitumor function of intratumoral CD8+ T cells, which can be applied to improve anti-PD-1 antibody therapy.
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Direct links to NCBI, no account and no request form: the whole study as GSE249184_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1047612 and SRA study SRP475361. Searching any of these in the dataset finder brings you back here.

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