STING1 orchestrates the injurious neuronal stress response
RNA-seq (gene expression) · mouse · 28 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 28 samples: 6 conditions, mostly with about 5 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- STING orchestrates the neuronal inflammatory stress response in multiple sclerosisCell · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE249192_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1047641 and SRA study SRP475390. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 28 samples.
How we read this: 6 replicated groups read from 28 sample titles; they account for 28 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7928004 IP_Acute_1 IP_Acute
- GSM7928005 IP_Acute_2 IP_Acute
- GSM7928006 IP_Acute_3 IP_Acute
- GSM7928007 IP_Acute_4 IP_Acute
- GSM7928008 IP_Acute_5 IP_Acute
- GSM7928009 IP_Chronic_1 IP_Chronic
- GSM7928010 IP_Chronic_2 IP_Chronic
- GSM7928011 IP_Chronic_3 IP_Chronic
- GSM7928012 IP_Chronic_4 IP_Chronic
- GSM7928013 IP_Health_1 IP_Health
- GSM7928014 IP_Health_2 IP_Health
- GSM7928015 IP_Health_3 IP_Health
- GSM7928016 IP_Health_4 IP_Health
- GSM7928017 IP_Health_5 IP_Health
- GSM7928018 Input_Acute_1 Input_Acute
- GSM7928019 Input_Acute_2 Input_Acute
- GSM7928020 Input_Acute_3 Input_Acute
- GSM7928021 Input_Acute_4 Input_Acute
- GSM7928022 Input_Acute_5 Input_Acute
- GSM7928023 Input_Chronic_1 Input_Chronic
- GSM7928024 Input_Chronic_2 Input_Chronic
- GSM7928025 Input_Chronic_3 Input_Chronic
- GSM7928026 Input_Chronic_4 Input_Chronic
- GSM7928027 Input_Health_1 Input_Health
- GSM7928028 Input_Health_2 Input_Health
- GSM7928029 Input_Health_3 Input_Health
- GSM7928030 Input_Health_4 Input_Health
- GSM7928031 Input_Health_5 Input_Health
- GSE267339 Transthyretin orchestrates vitamin B12-induced stress resilience [II] 16 samples shares orchestrates, stress
- GSE173999 Single-cel RNA-seq of Mouse Olfactory Epithelium for Understanding Age-associated Neuronal Injury Response 19 samples shares neuronal
- GSE312903 Connectome-seq: High-throughput Mapping of Neuronal Connectivity at Single-Synapse Resolution via Barcode Sequencing [snRNA-seq, ssRNA-seq] 47 samples shares neuronal
- GSE285978 Connectome-seq: High-throughput Mapping of Neuronal Connectivity at Single-Synapse Resolution via Barcode Sequencing 46 samples shares neuronal
- GSE306262 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [RNA-seq] 40 samples shares neuronal
- GSE255061 Phosphatase-independent activity of smooth-muscle calcineurin orchestrates a gene expression program leading to arterial hypertension 40 samples shares orchestrates
- GSE262587 TDG orchestrates ATF4-dependent gene transcription during retinoic acid-induced cell lineage committment 36 samples shares orchestrates
- GSE269318 Cancer-intrinsic Cxcl5 orchestrates global metabolic reprogramming of three dimensional cancers by upregulating Hif1α and Myc expression 31 samples shares orchestrates
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.