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LXR agonism enhances T cell activation upon crosspresentation by LXR-DKO BMDCs.

GSE249710 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2025/12/30 Platform GPL21103
Summary
Here, we analyze transcriptional profiles of OT-I CD8+ T cells co-cultured with LXR-/- bone marrow-derived dendritic cells pulsed with the SIINFEKL peptide in the absence or presence of the synthetic LXR agonist RGX-104.
Published in
Liver-X-receptor agonism enhances T cell priming and activation to promote anti-tumor immunity
Ostendorf BN, Goldstein JG, Liu S et al. · The Journal of experimental medicine 2026 · PMID 41665603 · doi:10.1084/jem.20252290
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Also filed as BioProject PRJNA1050218 and SRA study SRP476761. Searching any of these in the dataset finder brings you back here.

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