Human Hypertrophic Cardiomyopathy mRNA Profiling.
RNA-seq (gene expression) · human · 120 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 120 samples: 105 distinct titles, 5 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A multi-omics atlas of sex-specific differences in obstructive hypertrophic cardiomyopathyJournal of molecular and cellular cardiology · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE249925_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1051135 and SRA study SRP477383. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 120 sample titles: 105 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7967163 10
- GSM7967164 13
- GSM7967165 14
- GSM7967166 20
- GSM7967167 22
- GSM7967168 27
- GSM7967169 28
- GSM7967170 30
- GSM7967171 33
- GSM7967172 36
- GSM7967173 37
- GSM7967174 38
- GSM7967175 39
- GSM7967176 41
- GSM7967177 43
- GSM7967178 44
- GSM7967179 46
- GSM7967180 47
- GSM7967181 48
- GSM7967182 49
- GSM7967183 56
- GSM7967184 370118
- GSM7967185 587005
- GSM7967186 588103
- GSM7967187 610700
- GSM7967188 619278
- GSM7967189 629740
- GSM7967190 631131
- GSM7967191 631132
- GSM7967192 632093
- GSM7967193 633322
- GSM7967194 633573
- GSM7967195 634021
- GSM7967196 635263
- GSM7967197 638751
- GSM7967198 639124
- GSM7967199 639649
- GSM7967200 644621
- GSM7967201 645586
- GSM7967202 647526
+ 80 more — browse all 120 samples with per-sample file links →
- GSE337273 Transcriptomic signature of Human Cardiac Fibroblast in Hypertrophic Obstructive Cardiomyopathy 15 samples shares cardiomyopathy, hypertrophic
- GSE331527 Engineered heart tissues facilitate functional characterization of noncoding variants implicated in Hypertrophic and Dilated Cardiomyopathy [Bulk RNA-Seq] 15 samples shares cardiomyopathy, hypertrophic
- GSE276210 Beta-Adrenergic Stimulation and MYH7 G256E Mutant Gene Dosage Drive Hypertrophic Cardiomyopathy Phenotype Penetrance 14 samples shares cardiomyopathy, hypertrophic
- GSE191120 Next Generation Sequencing Facilitates Quantitative Analysis of Hypertrophic Cardiomyopathy/Healthy control Left Ventricular Transcriptomes 10 samples shares cardiomyopathy, hypertrophic
- GSE243406 Unravelling the etiology of dilated cardiomyopathy through differential miRNA-mRNA interactome 15 samples shares cardiomyopathy, mrna
- GSE328165 mRNA-based influenza vaccine expands the breadth of the B cell response in humans 109 samples shares mrna
- GSE252357 The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates MYC as a Hypertrophic Regulator 61 samples shares hypertrophic
- GSE277237 Auxin-induced depletion of human CCR4-NOT subunits reveals opposing functions of CNOT1 and CNOT4 in mRNA metabolism 48 samples shares mrna
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.