GEO series
ZNF292 genome-wide occupancy during cortical interneuron development
GSE249941
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing
31 samples
2025/02/05
GPL24676
Summary
Human embryonic stem cell (hESC) models of ZNF292 deficiency were generated, including a KRAB-only control and two CRISPRi knockdown models (ZNF-G1 and ZNF-G2). These hESC models were used to derived MGE-like ventral telencephalic neural progenitors (day 15; D15) and cortical interneurons (day 30; D30). CUT&Tag was utilized to define ZNF292 genome-wide occupancy at D15 and D30 during this process.
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Paper (PMID 40257863) ↗
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