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Study on the mechanism of DLX5 interaction with MYCN in the occurrence and development of neuroblastoma

GSE249951 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/12/01 Platform GPL24676
Summary
Neuroblastoma is the most common childhood tumor, which has high malignant degree and low survival rate, and seriously threatens the life and health of children. MYCN is a member of the MYC family and is closely associated with the development of neuroblastoma. In addition, DLX5 (Distal-Less Homeobox 5) also promotes cell proliferation by upregulating MYC promoter activity, but the role of DLX5 in neuroblastoma remains unclear. The aim of this study was to reveal the mechanism of DLX5 in the occurrence and development of neuroblastoma and to explore the targeted treatment strategy of neuroblastoma.
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Also filed as BioProject PRJNA1051172 and SRA study SRP477372. Searching any of these in the dataset finder brings you back here.

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