Spatial transcriptomics analysis identifies a unique tumor-promoting function of the meningeal stroma in melanoma leptomeningeal disease.

Direct links to NCBI, no account and no request form: the whole study as GSE250636_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1054687 and SRA study SRP479031. Searching any of these in the dataset finder brings you back here.

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+ 9 more — browse all 9 samples with per-sample file links →

• GSE286518 Integrative CSF profiling identifies disease-specific immune responses in leptomeningeal disease 42 samples
• GSE228360 Spatial and single cell transcriptomics reveals cellular crosstalk changes in ileal Crohn’s disease during inflammation 24 samples
• GSE320042 High-resolution and noninvasive profiling of the tumor microenvironment with spatial ecotypes 38 samples
• GSE189184 Divergent spatial microdomains drive inflammation and repair in Ulcerative and Immune Checkpoint Therapy Colitis - Spatial Transcriptomics 16 samples
• GSE270387 Single cell profiling of peripheral blood mononuclear cells in diverse men with prostate cancer reveals lethal disease-associated immune signatures 165 samples
• GSE325670 Promoter mutagenesis and a massively parallel reporter screen of the MAPT locus identifies cis-regulatory elements and genetic variation effects 140 samples
• GSE229733 Corticosteroid resistance is predetermined by early immune response dynamics at acute Graft-versus-Host disease onset 122 samples
• GSE279392 Single-cell RNA and TCR sequencing from skin, blood and cerebral spinal fluid (CSF) samples from Degos disease patients 116 samples

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