JMJD1C facilitates long distance genomic interactions by promoting condensates formation of key leukemic transcription factors in multiple AML cells
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 28 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 28 samples: 23 distinct titles, 4 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cellsProtein & cell · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE251729_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1055129 and SRA study SRP479310. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 28 sample titles: 23 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7986525 MOLM13, EGR1, 4C
- GSM7986526 CMK, JMJD1C
- GSM7986527 CMK, input
- GSM7986528 MOLM13, JMJD1C
- GSM7986529 MOLM13, input
- GSM7986530 MV4_11, JMJD1C
- GSM7986531 MV4_11, input
- GSM7986532 KG1, JMJD1C
- GSM7986533 MOLM13, RUNX1
- GSM7986534 Kasumi1, shNC, 1, JMJD1C
- GSM7986535 Kasumi1, shNC, 2, JMJD1C
- GSM7986536 Kasumi1, shRUNX1, 28, JMJD1C
- GSM7986537 Kasumi1, shRUNX1, 92, JMJD1C
- GSM7986538 Kasumi1, shRNA, input
- GSM7986539 MOLM13, shNC, 1, JMJD1C
- GSM7986540 MOLM13, shNC, 2, JMJD1C
- GSM7986541 MOLM13, shRUNX1, 59, JMJD1C
- GSM7986542 MOLM13, shRUNX1, 92, JMJD1C
- GSM7986543 MOLM13, shRNA, input
- GSM7986576 Kasumi1 cells, shRUNX1, 28
- GSM7986577 Kasumi1 cells, shRUNX1, 59
- GSM7986578 Kasumi1 cells, shRUNX1, 92
- GSM7986579 MOLM13 cells, shControl, 1
- GSM7986580 MOLM13 cells, shControl, 2
- GSM7986581 MOLM13 cells, shJMJD1C, 61
- GSM7986582 MOLM13 cells, shJMJD1C, 63
- GSM7986583 MOLM13 cells, shRUNX1, 28
- GSM7986584 MOLM13 cells, shRUNX1, 59
- GSE289435 Single-cell transcriptional atlas of hematopoiesis reveals genetic and hierarchy-based determinants of aberrant differentiation in AML 13 samples shares aml, transcription
- GSE319092 Integrated Multi-Omics and Interactome Analysis of CDK8 Inhibition Reveals Erythroid Differentiation Programs and BET Synergy in AML Stem-like Cells 135 samples shares aml
- GSE327386 RNA-Seq of paired diagnosis and relapse AML specimens with healthy controls 130 samples shares aml
- GSE287791 Single cell landscape of extramedullary AML 44 samples shares aml
- GSE282258 Imaging-based drug screening combined with moleuclar profiling identifies signatures and drivers of therapy resistance in pediatric AML [ATAC-seq] 44 samples shares aml
- GSE296381 Clonal evolution permits outgrowth of chemoresistant LMPP-like early progenitors in relapsed NPM1c AML 20 samples shares aml
- GSE303576 Rb-driven transcription limits its tumour suppressive effects in breast cancer 279 samples shares transcription
- GSE314310 Cardiopedia-Ligand: a Ligand Stimulation Atlas for Cardiac Function and Transcriptional Response 468 samples shares transcription
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.