GEO series
Expression Data from JAM-C or TAZ overexpressing ARPE-19 cells
GSE251997
Homo sapiens
Expression profiling by high throughput sequencing
10 samples
2025/12/30
GPL24676
Summary
Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is a hallmark of PVR, which remains an unresolved clinical challenge leading to vision loss. Here, we identified disregulation of junctional adhesion molecule C (JAM-C) and transcriptional co-activator with PDZ-binding motif (TAZ) as key regulators of RPE EMT.
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