Exploring molecular profiles of osteogenically differentiated aortic valvular interstitial cells
RNA-seq (gene expression) · human · 6 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 6 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE252266_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1059037 and SRA study SRP480668. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 6 more — browse all 6 samples with per-sample file links →
- GSE200600 Effects of KRAS (G13C) expression on transcriptome profiles assessed in HPCs differentiated from patient-derived iPS cells 12 samples shares differentiated, profiles
- GSE284183 Elevation of caldesmon-1 is essential for the differentiation of aortic valve interstitial cells into osteoblasts. 9 samples shares interstitial, aortic
- GSE214629 Analysis of the m6A methylome and downstream targets of piRNA AVCAPIR in human valvular interstitial cells 16 samples shares interstitial, valvular
- GSE295765 Circular ZBTB44-encoded ZBTB44-342aa alleviates osteogenic differentiation of human aortic valve interstitial cells by inhibiting the cGAS-STING pathway 11 samples shares interstitial, aortic
- GSE226482 Single cell RNA sequencing of spinal motor neurons and interneurons differentiated from isogenic FUS and TARDBP human induced pluripotent stem cell lines harbouring ALS-causative mutations 1415 samples shares differentiated
- GSE264196 A 50-gene high-risk profile predictive of COVID-19 and Idiopathic Pulmonary Fibrosis mortality originates from a molecular imbalance in monocyte and T-cell subsets that reverses in survivors with post-COVID-19 Interstitial Lung Disease 20 samples shares interstitial
- GSE303117 Exploring the biological basis for the identification of different syndromes in ischemic heart failure based on joint multi-omics analysis 129 samples shares exploring
- GSE221494 Cellular origin and clonal evolution of human dedifferentiated liposarcoma 84 samples shares differentiated
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.