RNA-seq of miR-34a-5p treated primary human vascular endothelial cells
RNA-seq (gene expression) · human · 8 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 8 samples: 4 × HUVEC, scrambled control, vs 4 × HUVEC, hsa-miR-34a-5p mimic,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE252957_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1063315 and SRA study SRP482959. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 8 samples.
How we read this: 2 replicated groups read from 8 sample titles; they account for 8 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8010950 HUVEC, scrambled control, rep1 HUVEC, scrambled contro…
- GSM8010951 HUVEC, scrambled control, rep2 HUVEC, scrambled contro…
- GSM8010952 HUVEC, scrambled control, rep3 HUVEC, scrambled contro…
- GSM8010953 HUVEC, scrambled control, rep4 HUVEC, scrambled contro…
- GSM8010954 HUVEC, hsa-miR-34a-5p mimic, rep1 HUVEC, hsa-miR-34a-5p m…
- GSM8010955 HUVEC, hsa-miR-34a-5p mimic, rep2 HUVEC, hsa-miR-34a-5p m…
- GSM8010956 HUVEC, hsa-miR-34a-5p mimic, rep3 HUVEC, hsa-miR-34a-5p m…
- GSM8010957 HUVEC, hsa-miR-34a-5p mimic, rep4 HUVEC, hsa-miR-34a-5p m…
- GSE327289 Cerebrovascular Single-Nucleus RNA-Seq Reveals Heat Shock Activation and Vascular Remodeling in Alzheimer’s Disease and Primary Tauopathies 76 samples shares vascular, rna-seq, primary
- GSE274335 RNA-Seq analysis LPCAT3 knockdown effect on primary human endometrial stromal cells(HESC). 6 samples shares rna-seq, primary
- GSE205154 Bulk RNA-Seq gene expression data for 289 primary and metastatic pancreatic ductal adenocarcinoma (PDAC) tumor samples from FFPE blocks. 289 samples shares rna-seq, primary
- GSE294300 Single-cell gene expression profiles of cells from primary colorectal cancer and adjacent normal tissue [scRNA-Seq] 36 samples shares rna-seq, primary
- GSE297742 Bulk RNA-seq of primary tumor biopsy samples from prostate adenocarcinoma patients 234 samples shares rna-seq, primary
- GSE339484 RNA-seq profiling of 14 paired primary and recurrent glioma cases 28 samples shares rna-seq, primary
- GSE296117 A single-cell RNA-seq dataset of synovial fluid from rheumatoid arthritis treated with TNF-α/JAK inhibitor 18 samples shares rna-seq, treated
- GSE312129 Single-nuclei multiome and spatial analyses of early, untreated SSc skin identify a proinflammatory vascular niche of macrophage-fibroblast signaling 38 samples shares vascular, treated
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.