GEO series
Transcriptional remodeling of human hematopoeitic stem cells in vitro by Interleukin-1β
GSE253764
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2024/11/05
GPL24676
Summary
Trained immunity is a phenomenon where innate immune cells develop and long-lasting pro-inflammatory reprogramming mediated by epigenetic and metabolic reprogramming. Trained immunity can be peropheral (circulating monocytes) or central (bone marrow) and it can be caused by exposure to β-glucan, BCG and Western Type Diet vial IL-1β signaling.
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Paper (PMID 39515317) ↗
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