Immunomodulatory effects of glucocorticoid-induced leucine zipper (GILZ) expression in murine bone-marrow derived macrophages.
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Immunomodulation by glucocorticoid-induced leucine zipper in macrophages: enhanced phagocytosis, protection from pyroptosis, and altered mitochondrial functionFrontiers in immunology · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE254137_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1068618 and SRA study SRP485757. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 6 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8034811 WT control_1 WT control
- GSM8034812 WT control_2 WT control
- GSM8034813 WT control_3 WT control
- GSM8034814 GILZ KO control_1 GILZ KO control
- GSM8034815 GILZ KO control_2 GILZ KO control
- GSM8034816 GILZ KO control_3 GILZ KO control
- GSM8034817 GILZ TG control_1 GILZ TG control
- GSM8034818 GILZ TG control_2 GILZ TG control
- GSM8034819 GILZ TG control_3 GILZ TG control
- GSM8034820 WT LPS_1 WT LPS
- GSM8034821 WT LPS_2 WT LPS
- GSM8034822 WT LPS_3 WT LPS
- GSM8034823 GILZ KO LPS_1 GILZ KO LPS
- GSM8034824 GILZ KO LPS_2 GILZ KO LPS
- GSM8034825 GILZ KO LPS_3 GILZ KO LPS
- GSM8034826 GILZ TG LPS_1 GILZ TG LPS
- GSM8034827 GILZ TG LPS_2 GILZ TG LPS
- GSM8034828 GILZ TG LPS_3 GILZ TG LPS
- GSE239479 AP-3-84 effects on gene expression in thioglycollate-induced, ID8 ascites or bone-marrow derived macrophages 48 samples shares bone-marrow, macrophages, derived
- GSE78849 Investigation of the effect of succinate and dimethyl malonate on murine bone-marrow derived macrophages (BMDMs) treated with or without LPS 21 samples shares bone-marrow, macrophages, derived
- GSE166050 RNA sequencing to profile transcriptomes in murine bone-marrow-derived macrophages upon infection with Leptospira spp. 18 samples shares bone-marrow, macrophages, derived
- GSE290443 Effects of WDFY3 overexpression on the transcriptomic profile of murine bone-marrow derived macrophages. 10 samples shares bone-marrow, macrophages, derived
- GSE301317 Differentially expressed genes in Bone-Marrow Derived Macrophages (M0) from DKO (Cdk8 flox/flox Vav-iCre Cdk19null) or VavCre control 8 samples shares bone-marrow, macrophages, derived
- GSE217269 RNA-seq analysis of Wild Type (WT) and Mettl3-/- (KO) BMDMs (bone-marrow-derived macrophages) Transcriptomes 6 samples shares bone-marrow, macrophages, derived
- GSE337254 Transcriptomic analysis of bone-marrow-derived macrophages treated with extracellular vesicles (EVs) from Aspergillus flavus 6 samples shares bone-marrow, macrophages, derived
- GSE336549 Effect of intravenous poly(lactide-co-glycolide) nanoparticles on M2-polarized bone-marrow derived macrophages 6 samples shares bone-marrow, macrophages, derived
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.