Synergizing Translational Repression Versus RNA Degradation by miRNAs during T Cell Activation
Non-coding RNA profiling · human · 27 samples
- What it is
- Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
- Organism
- Homo sapiens (human)
- Samples
- 27 samples: 21 distinct titles, 3 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- miRNA-Mediated Regulation of Gene Expression During Early Activation in Jurkat CellsbioRxiv : the preprint server for biology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE254231_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
Also filed as BioProject PRJNA1069038 and SRA study SRP485723. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 27 sample titles: 21 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8036204 Jurkat, 0h, rep1 (miRNA-Seq)
- GSM8036205 Jurkat, 0h, rep2 (miRNA-Seq)
- GSM8036206 Jurkat, 0h, rep3 (miRNA-Seq)
- GSM8036207 Jurkat, 12h, rep1 (miRNA-Seq)
- GSM8036208 Jurkat, 12h, rep2 (miRNA-Seq)
- GSM8036209 Jurkat, 12h, rep3 (miRNA-Seq)
- GSM8036210 Jurkat, 5h, rep1 (miRNA-Seq)
- GSM8036211 Jurkat, 5h, rep2 (miRNA-Seq)
- GSM8036212 Jurkat, 5h, rep3 (miRNA-Seq)
- GSM8036318 Jurkat, 0h, rep1 (RIBOseq)
- GSM8036319 Jurkat, 0h, rep2 (RIBOseq)
- GSM8036320 Jurkat, 0h, rep3 (RIBOseq)
- GSM8036321 Jurkat, 12h, rep1 (RIBOseq)
- GSM8036322 Jurkat, 12h, rep2 (RIBOseq)
- GSM8036323 Jurkat, 12h, rep3 (RIBOseq)
- GSM8036324 Jurkat, 5h, rep1 (RIBOseq)
- GSM8036325 Jurkat, 5h, rep2 (RIBOseq)
- GSM8036326 Jurkat, 5h, rep3 (RIBOseq)
- GSM8820663 Jurkat, 0h, rep1
- GSM8820664 Jurkat, 0h, rep2
- GSM8820665 Jurkat, 0h, rep3
- GSM8820666 Jurkat, 12h, rep1
- GSM8820667 Jurkat, 12h, rep2
- GSM8820668 Jurkat, 12h, rep3
- GSM8820669 Jurkat, 5h, rep1
- GSM8820670 Jurkat, 5h, rep2
- GSM8820671 Jurkat, 5h, rep3
- GSE328211 eIF3 interactions with miRNAs involved in translational control of early T cell activation 18 samples shares translational, activation, mirnas
- GSE100303 Histone demethylation and c-MYC activation enhance translational capacity in response to amino acid restriction [RNA-seq] 14 samples shares translational, activation
- GSE244655 Long read subcellular fractionation and sequencing reveals the translational fate of full length mRNA isoforms during neuronal differentiation 40 samples shares translational
- GSE227197 Translational and Transcriptional control of gene expression during serum stimulation on human RPE-1 cells 32 samples shares translational
- GSE271752 Macromolecular interactions dictate Polycomb-mediated epigenetic repression [ChIP-seq] 194 samples shares repression
- GSE281848 Ribosome biogenesis mediates the translational increase of codon non-optimal transcripts during IFN stimulation 24 samples shares translational
- GSE246931 Specific cPRC1 complexes are co-opted to mediate oncogenic gene repression in diffuse midline glioma 164 samples shares repression
- GSE307666 eIF3d and eIF3e mediate selective translational control of hypoxia that can be inhibited by small molecules 120 samples shares translational
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.