A pan-family screen of Nuclear Receptors in immunocytes reveals ligand-dependent inflammasome control [scRNA-seq]
Single-cell RNA-seq · mouse · 2 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Mus musculus (mouse)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome controlImmunity · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE254572_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1071071 and SRA study SRP486862. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE254406 A pan-family screen of Nuclear Receptors in immunocytes reveals ligand-dependent inflammasome control [RNA-seq 1] 52 samples shares ligand-dependent, inflammasome, immunocytes, pan-family, receptors, nuclear, control
- GSE273340 A pan-family screen of Nuclear Receptors in immunocytes reveals ligand-dependent inflammasome control [RNA-seq 2] 12 samples shares ligand-dependent, inflammasome, immunocytes, pan-family, receptors, nuclear, control
- GSE254573 A pan-family screen of Nuclear Receptors in immunocytes reveals ligand-dependent inflammasome control 70 samples shares ligand-dependent, inflammasome, immunocytes, pan-family, receptors, nuclear, control
- GSE254407 A pan-family screen of Nuclear Receptors in immunocytes reveals ligand-dependent inflammasome control [ChIPmentation] 4 samples shares ligand-dependent, inflammasome, immunocytes, pan-family, receptors, nuclear, control
- GSE274312 A cis-regulatory element controls HDAC9 expression to fine-tune inflammasome-dependent chronic inflammation 24 samples shares inflammasome, control
- GSE207875 Nuclear Receptor Coactivator 6 is a Critical Regulator of NLRP3 Inflammasome Activation and Gouty Arthritis 8 samples shares inflammasome, nuclear
- GSE278604 Neutrophil KLF2 regulates inflammasome-dependent neonatal mortality from endotoxemia 28 samples shares inflammasome
- GSE320220 microRNA146a suppresses pancreatitis via cross-talk with NF-kB and ASC-containing inflammasomes 20 samples shares inflammasome
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.