G3BP2B stress granules regulate mRNA expression under ER stress [RNAseq_Exp2]
RNA-seq (gene expression) · human · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples: 10 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- G3BP isoforms differentially affect stress granule assembly and gene expression during cellular stressMolecular biology of the cell · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE254629_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1071162 and SRA study SRP486945. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 10 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8047386 RNAseq_U2OSwt_DMSO_Rep1 RNAseq_U2OSwt_DMSO
- GSM8047387 RNAseq_U2OSwt_DMSO_Rep2 RNAseq_U2OSwt_DMSO
- GSM8047388 RNAseq_U2OS_G3BPKO_DMSO_Rep1 RNAseq_U2OS_G3BPKO_DMSO
- GSM8047389 RNAseq_U2OS_G3BPKO_DMSO_Rep2 RNAseq_U2OS_G3BPKO_DMSO
- GSM8047390 RNAseq_U2OS_G3BP1wt_DMSO_Rep1 RNAseq_U2OS_G3BP1wt_DMSO
- GSM8047391 RNAseq_U2OS_G3BP1wt_DMSO_Rep2 RNAseq_U2OS_G3BP1wt_DMSO
- GSM8047392 RNAseq_U2OS_G3BP2A_DMSO_Rep1 RNAseq_U2OS_G3BP2A_DMSO
- GSM8047393 RNAseq_U2OS_G3BP2A_DMSO_Rep2 RNAseq_U2OS_G3BP2A_DMSO
- GSM8047394 RNAseq_U2OS_G3BP2B_DMSO_Rep1 RNAseq_U2OS_G3BP2B_DMSO
- GSM8047395 RNAseq_U2OS_G3BP2B_DMSO_Rep2 RNAseq_U2OS_G3BP2B_DMSO
- GSM8047396 RNAseq_U2OSwt_Thaps_Rep1 RNAseq_U2OSwt_Thaps
- GSM8047397 RNAseq_U2OSwt_Thaps_Rep2 RNAseq_U2OSwt_Thaps
- GSM8047398 RNAseq_U2OS_G3BPKO_Thaps_Rep1 RNAseq_U2OS_G3BPKO_Thaps
- GSM8047399 RNAseq_U2OS_G3BPKO_Thaps_Rep2 RNAseq_U2OS_G3BPKO_Thaps
- GSM8047400 RNAseq_U2OS_G3BP1wt_Thaps_Rep1 RNAseq_U2OS_G3BP1wt_Tha…
- GSM8047401 RNAseq_U2OS_G3BP1wt_Thaps_Rep2 RNAseq_U2OS_G3BP1wt_Tha…
- GSM8047402 RNAseq_U2OS_G3BP2A_Thaps_Rep1 RNAseq_U2OS_G3BP2A_Thaps
- GSM8047403 RNAseq_U2OS_G3BP2A_Thaps_Rep2 RNAseq_U2OS_G3BP2A_Thaps
- GSM8047404 RNAseq_U2OS_G3BP2B_Thaps_Rep1 RNAseq_U2OS_G3BP2B_Thaps
- GSM8047405 RNAseq_U2OS_G3BP2B_Thaps_Rep2 RNAseq_U2OS_G3BP2B_Thaps
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- GSE309705 Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma 274 samples shares regulate
- GSE309698 Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma [RNA-Seq] 246 samples shares regulate
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.