PI3Kg inhibition circumvents inflammation and mortality in SARS-CoV-2 and other infections

Direct links to NCBI, no account and no request form: the whole study as GSE255211_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 7 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1073955 and SRA study SRP488514. Searching any of these in the dataset finder brings you back here.

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• GSE300288 Single-cell and spatial transcriptomics analysis of tobacco-associated lung adenocarcinoma development, and in response to targeting inflammation alone or in combination with immune checkpoint blockade in precancerous phase [scRNA-seq] 31 samples
• GSE337190 CAR-NKT cells induce low cytokine release syndrome by targeting hyperinflammatory macrophages with mitigation from GM-SCF inhibition. 24 samples
• GSE304706 Persistent ER stress in macrophages fuels age-related inflammation and vulnerability to infection 8 samples
• GSE314817 Multi-tissue, multi-time-point transcriptomic atlas of aging in mice and rats [mouse] 2432 samples
• GSE293709 Transcriptome analysis in the prefrontal cortex of different ASD mouse models treated with drug 1565 samples
• GSE294832 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part10] 1000 samples
• GSE326100 scRNA-seq of mouse cochlea organoid cells 768 samples

Search all mouse RNA-seq datasets in GEO →