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RNA-binding protein RPS27 and gene expression regulation in human umbilical vein endothelial cells (HUVECs)

GSE255600 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/03/31 Platform GPL24676
Summary
RPS27, a significantly down-regulated and validated RBP in kaposi's sarcoma (KS), and known to be associated with viral infection. As KS is an endothelial cell cancer, we used HUVECs as the cell model to explore the functions of RPS27. RNA-seq technology was used to investigate the differentially expressed genes in HUVECs. By using small interference RNAs (siRNAs) to silence the expression of RPS27 (siRPS27), we detected significant decrease of RPS27 expression in RNA levels comparing with the negative control (siNC) samples.
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Direct links to NCBI, no account and no request form: the whole study as GSE255600_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1075739 and SRA study SRP489696. Searching any of these in the dataset finder brings you back here.

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