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ChIP–seq on periosteal cells derived from the pre-invasive group using antibodies to acetylated histone H3 Lys27 (H3K27ac), H3K4me3 and HIF-1α

GSE256307 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 4 samples Submitted 2024/06/17 Platform GPL24247
Summary
To test whether HIF-1a can directly induce Timp1 expression in periosteal cells at the pre-invasive stage of head and neck squamous cell carcinoma (HNSCC), we performed Chromatin immunoprecipitation followed by sequencing (ChIP–seq) on periosteal cells derived from the pre-invasive stage of a mouse HNSCC bone invasion model by using antibodies to acetylated histone H3 Lys27 (H3K27ac), H3K4me3 and HIF-1α.
Published in
The periosteum provides a stromal defence against cancer invasion into the bone
Nakamura K, Tsukasaki M, Tsunematsu T et al. · Nature 2024 · PMID 39169177 · doi:10.1038/s41586-024-07822-1
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Also filed as BioProject PRJNA1078933 and SRA study SRP490893. Searching any of these in the dataset finder brings you back here.

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