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Total RNA sequencing data for transcriptomic analysis of the effect of chronic ethanol administration on mouse testis

GSE256349 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/05/24 Platform GPL21103
Summary
Alcohol is a widely consumed beverage in human society, but it can cause toxic effects.Previous studies on the effects of alcohol consumption on male reproductive function have focused solely on hormonal regulation and physiological changes. However, spermatogenesis is a complex process that requires systemic regulation, including intrinsic regulation by germ cell-specific genes.This study presents a transcriptomic analysis of the effect of chronic ethanol administration on mouse testes.The administration of ethanol to the testis resulted in several alterations in the transcription of testicular genes. Although the changes in expression were mild, a group of genes related to sperm were observed.
Published in
Ethanol-related transcriptomic changes in mouse testes
Han G, Lee SJ, Hong SP et al. · BMC genomics 2024 · PMID 39164623 · doi:10.1186/s12864-024-10696-2
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Direct links to NCBI, no account and no request form: the whole study as GSE256349_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1079240 and SRA study SRP491004. Searching any of these in the dataset finder brings you back here.

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