Analysis of a pair of HCA-7 derived cells with low expressing (CC) or high expressing (CC-CR) levels of miR-100 and miR-125b and RNA collected from Ago2 RNA immunoprecipitation
Non-coding RNA profiling · human · 22 samples
- What it is
- Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
- Organism
- Homo sapiens (human)
- Samples
- 22 samples: 8 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transfer of miR-100 and miR-125b increases 3D growth and invasiveness in recipient cancer cellsExtracellular vesicles and circulating nucleic acids · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE259372_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
Also filed as BioProject PRJNA1081376 and SRA study SRP492044. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 22 samples.
How we read this: 8 replicated groups read from 22 sample titles; they account for 22 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8114933 CCCR_WC_1 CCCR_WC
- GSM8114934 CCCR_WC_2 CCCR_WC
- GSM8114935 CCCR_WC_3 CCCR_WC
- GSM8114936 CC_WC_1 CC_WC
- GSM8114937 CC_WC_2 CC_WC
- GSM8114938 CC_WC_3 CC_WC
- GSM8114939 CCCR_Ago2_RIP_1 CCCR_Ago2_RIP
- GSM8114940 CCCR_Ago2_RIP_2 CCCR_Ago2_RIP
- GSM8114941 CCCR_Ago2_RIP_3 CCCR_Ago2_RIP
- GSM8114942 CC_Ago2_RIP_1 CC_Ago2_RIP
- GSM8114943 CC_Ago2_RIP_3 CC_Ago2_RIP
- GSM8114944 CCCR_WC_ncRNA-seq1 CCCR_WC_ncRNA-seq
- GSM8114945 CCCR_WC_ncRNA-seq2 CCCR_WC_ncRNA-seq
- GSM8114946 CCCR_WC_ncRNA-seq3 CCCR_WC_ncRNA-seq
- GSM8114947 CC_WC_ncRNA-seq1 CC_WC_ncRNA-seq
- GSM8114948 CC_WC_ncRNA-seq2 CC_WC_ncRNA-seq
- GSM8114949 CC_WC_ncRNA-seq3 CC_WC_ncRNA-seq
- GSM8114950 CCCR_Ago2_RIP_ncRNA-seq1 CCCR_Ago2_RIP_ncRNA-seq
- GSM8114951 CCCR_Ago2_RIP_ncRNA-seq3 CCCR_Ago2_RIP_ncRNA-seq
- GSM8114952 CC_Ago2_RIP_ncRNA-seq1 CC_Ago2_RIP_ncRNA-seq
- GSM8114953 CC_Ago2_RIP_ncRNA-seq2 CC_Ago2_RIP_ncRNA-seq
- GSM8114954 CC_Ago2_RIP_ncRNA-seq3 CC_Ago2_RIP_ncRNA-seq
- GSE259370 Analysis of a pair of HCA-7 derived cells with low expressing (CC) or high expressing (CC-CR) levels of miR-100 and miR-125b and RNA collected from Ago2 RNA immunoprecipitation (RNAseq_human_AGO2_IP.8635) 11 samples shares mir-125b, mir-100, hca-7, cc-cr, ago2, immunoprecipitation, expressing, collected
- GSE259375 Analysis of an HCA-7 derived cell line (CC-CR) and cell lines generated with knockout of miR-100, miR-125b, or both miRNAs. 60 samples shares mir-125b, mir-100, hca-7, cc-cr
- GSE259373 Analysis of an HCA-7 derived cell line (CC-CR) and cell lines generated with knockout of miR-100, miR-125b, or both miRNAs (RNAseq_human_miR_KO.7223) 30 samples shares mir-125b, mir-100, hca-7, cc-cr
- GSE305290 Largazole targets Musashi protein expression via miR-125b-5p and sensitizes triple-negative breast cancer cells to irradiation 6 samples shares mir-125b
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.