Analysis of an HCA-7 derived cell line (CC-CR) and cell lines generated with knockout of miR-100, miR-125b, or both miRNAs.
Non-coding RNA profiling · human · 60 samples
- What it is
- Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
- Organism
- Homo sapiens (human)
- Samples
- 60 samples: 20 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transfer of miR-100 and miR-125b increases 3D growth and invasiveness in recipient cancer cellsExtracellular vesicles and circulating nucleic acids · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE259375_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
Also filed as BioProject PRJNA1081375 and SRA study SRP492051. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 60 samples.
How we read this: 20 replicated groups read from 60 sample titles; they account for 60 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8114955 A12_1 A12
- GSM8114956 A12_3 A12
- GSM8114957 A12_4 A12
- GSM8114958 A13_1 A13
- GSM8114959 A13_3 A13
- GSM8114960 A13_4 A13
- GSM8114961 A17_1 A17
- GSM8114962 A17_3 A17
- GSM8114963 A17_4 A17
- GSM8114964 A22_1 A22
- GSM8114965 A22_3 A22
- GSM8114966 A22_4 A22
- GSM8114967 B30_1 B30
- GSM8114968 B30_3 B30
- GSM8114969 B30_4 B30
- GSM8114970 B34_1 B34
- GSM8114971 B34_3 B34
- GSM8114972 B34_4 B34
- GSM8114973 C55_1 C55
- GSM8114974 C55_3 C55
- GSM8114975 C55_4 C55
- GSM8114976 D82_1 D82
- GSM8114977 D82_3 D82
- GSM8114978 D82_4 D82
- GSM8114979 D84_1 D84
- GSM8114980 D84_3 D84
- GSM8114981 D84_4 D84
- GSM8114982 CCCR_1 CCC
- GSM8114983 CCCR_3 CCC
- GSM8114984 CCCR_4 CCC
- GSM8114985 A12_ncRNA-seq_1 A12_ncRNA-seq
- GSM8114986 A12_ncRNA-seq_3 A12_ncRNA-seq
- GSM8114987 A12_ncRNA-seq_4 A12_ncRNA-seq
- GSM8114988 A13_ncRNA-seq_1 A13_ncRNA-seq
- GSM8114989 A13_ncRNA-seq_3 A13_ncRNA-seq
- GSM8114990 A13_ncRNA-seq_4 A13_ncRNA-seq
- GSM8114991 A17_ncRNA-seq_1 A17_ncRNA-seq
- GSM8114992 A17_ncRNA-seq_3 A17_ncRNA-seq
- GSM8114993 A17_ncRNA-seq_4 A17_ncRNA-seq
- GSM8114994 A22_ncRNA-seq_1 A22_ncRNA-seq
+ 20 more — browse all 60 samples with per-sample file links →
- GSE259373 Analysis of an HCA-7 derived cell line (CC-CR) and cell lines generated with knockout of miR-100, miR-125b, or both miRNAs (RNAseq_human_miR_KO.7223) 30 samples shares mir-125b, mir-100, hca-7, cc-cr, generated, knockout, derived, mirnas
- GSE259372 Analysis of a pair of HCA-7 derived cells with low expressing (CC) or high expressing (CC-CR) levels of miR-100 and miR-125b and RNA collected from Ago2 RNA immunoprecipitation 22 samples shares mir-125b, mir-100, hca-7, cc-cr, derived
- GSE259370 Analysis of a pair of HCA-7 derived cells with low expressing (CC) or high expressing (CC-CR) levels of miR-100 and miR-125b and RNA collected from Ago2 RNA immunoprecipitation (RNAseq_human_AGO2_IP.8635) 11 samples shares mir-125b, mir-100, hca-7, cc-cr, derived
- GSE305290 Largazole targets Musashi protein expression via miR-125b-5p and sensitizes triple-negative breast cancer cells to irradiation 6 samples shares mir-125b
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.