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The effect of high fat diet on mouse prostate development

GSE260450 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/03/03 Platform GPL19057
Summary
Steroid 5α reductase 2 (SRD5A2) is the predominant enzyme responsible for prostatic development and growth. Despite the introduction of steroid 5α-reductase inhibitors (5ARI) for benign prostatic hyperplasia (BPH), the progression of LUTS is only slowed by 34% with 5ARI-response. Previous literature establishes link between obesity and BPH progression. We hypothesize that high fat diet is associated with prostate development.
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Direct links to NCBI, no account and no request form: the whole study as GSE260450_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1081784 and SRA study SRP492271. Searching any of these in the dataset finder brings you back here.

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