← BioTransfer GEO Dataset Finder
GEO series

T-bet deficiency and Hic1 induction override TGF-b-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells

GSE260630 Mus musculus Expression profiling by high throughput sequencing 9 samples Submitted 2024/03/10 Platform GPL24247
Summary
TGF-beta signaling is required for the differentiation of gut-resident memory CD8 T cells. Here, we showed that the deficiency of transcription factor T-bet partially rescued the differentiation of TGF-beta receptor deficient gut-resident memory CD8 T cells. Hic1 induction further strengthens TRM maturation in the absence of TGF-b and T-bet.
Published in
T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103(+) intestine-resident memory CD8(+) T cells
Wang L, Mishra S, Fan KK et al. · Cell reports 2024 · PMID 38781073 · doi:10.1016/j.celrep.2024.114258
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE260630_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1082371 and SRA study SRP492692. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 9 more — browse all 9 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.