Impact of c-JUN deficiency on thalamus development in mice and human neural models [ATACseq, RNAseq, CUT&Tag]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 23 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 23 samples: 23 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Impact of c-JUN deficiency on thalamus development in mice and human neural modelsCell & bioscience · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE260732_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1083042 and SRA study SRP492977. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 23 sample titles: 23 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8123113 1_ThO_H1WT_D20_ATACseq
- GSM8123114 2_ThO_H1cJunKO_D20_ATACseq
- GSM8123115 3_ThO_H1cJunKO+cJun_D20_ATACseq
- GSM8123116 4_ThO_H1WT_D25_ATACseq
- GSM8123117 5_ThO_H1cJunKO_D25_ATACseq
- GSM8123118 6_ThO_H1cJunKO+cJun_D25_ATACseq
- GSM8123119 7_ThO_H1WT_D30_ATACseq
- GSM8123120 8_ThO_H1cJunKO_D30_ATACseq
- GSM8123121 9_ThO_H1cJunKO+cJun_D30_ATACseq
- GSM8123122 1_ThO-1_H1WT_D25_RNAseq_rp1
- GSM8123123 2_ThO-2_H1WT_D25_RNAseq_rp2
- GSM8123124 3_ThO-3_H1cJunKO_D25_RNAseq_rp1
- GSM8123125 4_ThO-4_H1cJunKO_D25_RNAseq_rp2
- GSM8123126 5_ThO-5_H1cJunKO+cJun_D25_RNAseq_rp1
- GSM8123127 6_ThO-6_H1cJunKO+cJun_D25_RNAseq_rp2
- GSM8123128 7_ThO-7_H1WT_D30_RNAseq_rp1
- GSM8123129 8_ThO-8_H1WT_D30_RNAseq_rp2
- GSM8123130 9_ThO-9_H1cJunKO_D30_RNAseq_rp1
- GSM8123131 10_ThO-10_H1cJunKO_D30_RNAseq_rp2
- GSM8123132 11_ThO-11_H1cJunKO+cJun_D30_RNAseq_rp1
- GSM8123133 12_ThO-12_H1cJunKO+cJun_D30_RNAseq_rp2
- GSM8123134 1_ThO_H1WT_D25_CUTtag
- GSM8123135 3_ThO_H1cJunKO+cJun_D25_CUTtag
- GSE251919 Mutant NPM1 marginally impacts ribosome footprint in acute myeloid leukemia cells 12 samples shares cut, impact
- GSE241581 DCAF15 control of cohesin dynamics sustains acute myeloid leukemia 36 samples shares cut
- GSE342612 Transcriptomic and H3K27ac chromatin responses of human microglia to acute PFOS exposure and recovery 36 samples shares cut
- GSE324154 Therapy Induced Senescence Promotes Immunogenicity in Acute Myeloid Leukemia through Reduced EZH2 Activity 22 samples shares cut
- GSE278751 A stem cell model identifies two alternative cell fates in CBFA2T3::GLIS2-driven acute megakaryoblastic leukemia initiation (Multiome scRNA-seq/scATAC-seq) 14 samples shares cut
- GSE239775 Quantification of Systemic Inflammation by a Gene Score Uncovers Relevant Features on Acutely Decompensated Cirrhosis 1177 samples shares cut
- GSE243299 3D Chromatin Remodeling in B-cell Development and B-cell Acute Lymphoblastic Leukemia 112 samples shares cut
- GSE268035 STAG2 Mutations Reshape the Cohesin-Structured Spatial Chromatin Architecture to Drive Gene Regulation in Acute myeloid Leukemia 541 samples shares cut
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.