GEO series
Ifi27l2a regulates the microglial inflammation in the context of aging and stroke
GSE261494
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2025/01/09
GPL19057
Summary
Microglia are key mediators of inflammatory responses within the brain, as they regulate pro-inflammatory responses while also limiting neuroinflammation via reparative phagocytosis. To facilitate identification of potential mediators of inflammation, we performed single-cell RNA sequencing of aged mouse brains following stroke and found that Ifi27l2a was significantly up-regulated, particularly in microglia.
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Paper (PMID 39953063) ↗
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