Pericardial Fluid of Patients with Coronary Artery Disease Can Drive Fibrosis via TGF-Beta Signalling Pathway
RNA-seq (gene expression) · human · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples: 17 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Pericardial Fluid of Patients With Coronary Artery Disease Can Drive Fibrosis Via TGF-Beta PathwayJACC. Basic to translational science · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE262161_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1090494 and SRA study SRP497041. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 24 sample titles: 17 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8158965 Myocardian fibroblast, cultured, subject tp308
- GSM8158966 Myocardian fibroblast, cultured, subject tp308, PF supernatant treated
- GSM8158967 Myocardian fibroblast, cultured, subject tp308, PF supernatant and TGFbR1i treated
- GSM8158968 Myocardian fibroblast, cultured, subject tp300
- GSM8158969 Myocardian fibroblast, cultured, subject tp300, PF supernatant treated
- GSM8158970 Myocardian fibroblast, cultured, subject tp300, PF supernatant and TGFbR1i treated
- GSM8158971 Myocardian fibroblast, cultured, subject tp307
- GSM8158972 Myocardian fibroblast, cultured, subject tp307, PF supernatant treated
- GSM8158973 Myocardian fibroblast, cultured, subject tp307, PF supernatant and TGFbR1i treated
- GSM8158974 Myocardian fibroblast, cultured, subject tp320
- GSM8158975 Myocardian fibroblast, cultured, subject tp320, PF supernatant treated
- GSM8158976 Myocardian fibroblast, cultured, subject tp320, PF supernatant and TGFbR1i treated
- GSM8158977 Myocardian fibroblast, cultured, subject tp323
- GSM8158978 Myocardian fibroblast, cultured, subject tp323, PF supernatant treated
- GSM8158979 Myocardian fibroblast, cultured, subject tp323, PF supernatant and TGFbR1i treated
- GSM8158980 Myocardian fibroblast, cultured, subject tp321
- GSM8158981 Myocardian fibroblast, cultured, subject tp321, PF supernatant treated
- GSM8158982 Myocardian fibroblast, cultured, subject tp321, PF supernatant and TGFbR1i treated
- GSM8158983 Myocardian fibroblast, cultured, subject tp393
- GSM8158984 Myocardian fibroblast, cultured, subject tp393, PF supernatant treated
- GSM8158985 Myocardian fibroblast, cultured, subject tp393, PF supernatant and TGFbR1i treated
- GSM8158986 Myocardian fibroblast, cultured, subject tp410
- GSM8158987 Myocardian fibroblast, cultured, subject tp410, PF supernatant treated
- GSM8158988 Myocardian fibroblast, cultured, subject tp410, PF supernatant and TGFbR1i treated
- GSE263306 Imbalanced TGF-beta signalling and autophagy drive erythroid priming of hematopoietic stem cells in Beta-thalassemia 20 samples shares tgf-beta, drive
- GSE310095 Whole Blood Transcriptomics Differentiates Circulating Gene Expression Between Coronary Artery Disease and Peripheral Artery Disease 71 samples shares coronary, artery
- GSE289957 Differential Gene Expression related to Telomere Length in Arterial Wall Tissues and Granulocytes of Patients with Coronary Artery Disease 34 samples shares coronary, artery
- GSE275145 Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures [Human scRNA-seq] 29 samples shares fibrosis, drive
- GSE237851 CD14 Serves as a Predicted Marker for Coronary Artery Lesions in Kawasaki Disease 24 samples shares coronary, artery
- GSE290015 Amniotic Fluid Reduces Liver Fibrosis By Attenuating Hepatic Stellate Cell Activation 21 samples shares fibrosis, fluid
- GSE311133 Transcriptome analysis of human coronary artery smooth muscle cells under pro-differentiation and pro-dedifferentiation treatments 15 samples shares coronary, artery
- GSE278420 Senolytic and anti-inflammatory efficacy of quercetin in men and women undergoing coronary artery by-pass surgery 12 samples shares coronary, artery
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.