GEO series
Genomic positioning in LBR and Lamin A K562 knockout cells
GSE263012
Homo sapiens
Expression profiling by high throughput sequencing; Other
38 samples
2024/04/04
GPL16791GPL24676
Summary
To probe the functional consequences of nuclear lamina genome association, we made LMNA, LBR, and double LMNA/LBR K562 knockout lines. We first examined the genome interaction changes with nulcear lamina using LMNB1 DamID seq and further assessed the functional consequences of these changes using RNA-seq and repli-seq.
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