GEO series
Single nucleus RNA sequencing of the cerebral cortex from genetically diverse inbred mouse strains reveals differences in pericyte and endothelial cell composition
GSE263649
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2025/07/30
GPL24247
Summary
Genetic background influences animal behavior and susceptibility to brain diseases. To evaluate how genetic background influences the relative number and/or types of cells in the brain, we performed single nucleus RNA sequencing on 14 genetically distinct collaborative cross (CC) inbred mouse strains. These data comprise over 287,000 nuclei derived from 92 samples across each of the strains. We identified 11 principal cell types and 59 refined cell types in each of the strains.
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Paper (PMID 40875631) ↗
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