3`mRNA sequencing of splenic RNA (MACE) at the 30h time point after acetaminophen (APAP) 300mg/kg administration
RNA-seq (gene expression) · mouse · 2 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Targeting cathepsin C ameliorates murine acetaminophen-induced liver injuryTheranostics · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE263675_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1098746 and SRA study SRP500808. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE263673 3`mRNA sequencing of liver RNA (MACE) at the 30h time point after acetaminophen (APAP) 300mg/kg administration 2 samples shares 300mg, mace, apap, administration, acetaminophen, point, mrna
- GSE304809 Curative treatment of advanced, poorly immunogenic metastatic murine cancer models using an in situ vaccine, low-dose radiopharmaceutical, and immune checkpoint inhibition 14 samples shares mace, point
- GSE275609 Tumor immunity following radiopharmaceutical + checkpoint blockade varies with treatment sequence, radioisotope, and tumor immunogenicity 10 samples shares mace, point
- GSE261665 Effect of oral administration of Si-based agent on renal mRNA expression. 15 samples shares administration, mrna
- GSE249674 Intratumoral administration of lipid nanoparticles carrying mRNA encoding for IL-21, IL-7, and 4-1BBL induces anti-tumor immunity in preclinical tumor models. 6 samples shares administration, mrna
- GSE311819 Single cell mRNA sequencing on esophageal cells of WT and Krt5-CreERT2:R26SmoM2/EYFP (K5:Smo) mice 5 days after Tamoxifen administration 2 samples shares administration, mrna
- GSE235586 Transcriptomic analysis of 30dpp ovaries and 35dpp testes exposed to the cocktails of pharmaceuticals ibuprofen (IBU), 2hydroxyIBU (2hIBU), diclofenac (DCF) and 17a ethinyl-estradiol (EE2) in mice 54 samples shares mace
- GSE246193 Genetic and pharmaceutical targeting of Suv39h1 ameliorates renal fibrosis by unlocking CXCL10 transcription 22 samples shares mace
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.