Single cell mRNA sequencing on esophageal cells of WT and Krt5-CreERT2:R26SmoM2/EYFP (K5:Smo) mice 5 days after Tamoxifen administration
Single-cell RNA-seq · mouse · 2 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Mus musculus (mouse)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Intrinsic mechanisms and microenvironmental cues fine-tune plasticity of esophageal progenitorsNature communications · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE311819_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1370951 and SRA study SRP649760. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE291095 mRNA sequencing on esophageal cells of Krt5-CreERT2:R26SmoM2/EYFP (K5:Smo) mice, untreated and treated with ibuprofen 6 samples shares r26smom2, eyfp, krt5-creert2, esophageal, mrna
- GSE291090 Single cell mRNA sequencing on esophageal cells of Krt5-CreERT2:R26SmoM2/EYFP (K5:Smo) mice untreated and treated with ibuprofen 2 samples shares r26smom2, eyfp, krt5-creert2, esophageal, mrna
- GSE261665 Effect of oral administration of Si-based agent on renal mRNA expression. 15 samples shares administration, mrna
- GSE249674 Intratumoral administration of lipid nanoparticles carrying mRNA encoding for IL-21, IL-7, and 4-1BBL induces anti-tumor immunity in preclinical tumor models. 6 samples shares administration, mrna
- GSE263673 3`mRNA sequencing of liver RNA (MACE) at the 30h time point after acetaminophen (APAP) 300mg/kg administration 2 samples shares administration, mrna
- GSE263675 3`mRNA sequencing of splenic RNA (MACE) at the 30h time point after acetaminophen (APAP) 300mg/kg administration 2 samples shares administration, mrna
- GSE272289 Adverse proinflammatory responses in the kidney after FGF23 administration in murine kidney disease models 38 samples shares administration
- GSE266470 Selective targeting and modulation of plaque associated microglia via systemic hydroxyl dendrimer administration in an Alzheimer’s disease mouse model. 32 samples shares administration
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.