RNA-seq of O4+ oligodendrocyte progenitors isolated from P5 and P60 mice
RNA-seq (gene expression) · mouse · 32 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 32 samples: 8 conditions, mostly with about 5 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitorsThe Journal of cell biology · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE263808_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1099270 and SRA study SRP501307. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 32 samples.
How we read this: 8 replicated groups read from 32 sample titles; they account for 32 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8199498 Untreated O4+ aOPC rep1 Untreated O4+ aOPC
- GSM8199499 Untreated O4+ aOPC rep2 Untreated O4+ aOPC
- GSM8199500 DMSO O4+ aOPC rep1 DMSO O4+ aOPC
- GSM8199501 DMSO O4+ aOPC rep2 DMSO O4+ aOPC
- GSM8199502 DMSO O4+ aOPC rep3 DMSO O4+ aOPC
- GSM8199503 DMSO O4+ aOPC rep4 DMSO O4+ aOPC
- GSM8199504 KATi O4+ aOPC rep1 KATi O4+ aOPC
- GSM8199505 KATi O4+ aOPC rep2 KATi O4+ aOPC
- GSM8199506 KATi O4+ aOPC rep3 KATi O4+ aOPC
- GSM8199507 KATi O4+ aOPC rep4 KATi O4+ aOPC
- GSM8199508 SUV420i O4+ aOPC rep1 SUV420i O4+ aOPC
- GSM8199509 SUV420i O4+ aOPC rep2 SUV420i O4+ aOPC
- GSM8199510 SUV420i O4+ aOPC rep3 SUV420i O4+ aOPC
- GSM8199511 SUV420i O4+ aOPC rep4 SUV420i O4+ aOPC
- GSM8199512 Untreated O4+ nOPC rep1 Untreated O4+ nOPC
- GSM8199513 Untreated O4+ nOPC rep2 Untreated O4+ nOPC
- GSM8199514 Untreated O4+ nOPC rep3 Untreated O4+ nOPC
- GSM8199515 DMSO O4+ nOPC rep1 DMSO O4+ nOPC
- GSM8199516 DMSO O4+ nOPC rep2 DMSO O4+ nOPC
- GSM8199517 DMSO O4+ nOPC rep3 DMSO O4+ nOPC
- GSM8199518 DMSO O4+ nOPC rep4 DMSO O4+ nOPC
- GSM8199519 DMSO O4+ nOPC rep5 DMSO O4+ nOPC
- GSM8199520 KATi O4+ nOPC rep1 KATi O4+ nOPC
- GSM8199521 KATi O4+ nOPC rep2 KATi O4+ nOPC
- GSM8199522 KATi O4+ nOPC rep3 KATi O4+ nOPC
- GSM8199523 KATi O4+ nOPC rep4 KATi O4+ nOPC
- GSM8199524 KATi O4+ nOPC rep5 KATi O4+ nOPC
- GSM8199525 SUV420i O4+ nOPC rep1 SUV420i O4+ nOPC
- GSM8199526 SUV420i O4+ nOPC rep2 SUV420i O4+ nOPC
- GSM8199527 SUV420i O4+ nOPC rep3 SUV420i O4+ nOPC
- GSM8199528 SUV420i O4+ nOPC rep4 SUV420i O4+ nOPC
- GSM8199529 SUV420i O4+ nOPC rep5 SUV420i O4+ nOPC
- GSE291697 RNA-Seq experiments for isolated mice tissues in both WT and Mut mice 32 samples shares isolated, rna-seq
- GSE326003 The differentiation of myeloid progenitors is effected by cascading waves of coordinated gene expression that remodel cellular physiology in a characteristic sequence [RNA-seq] 165 samples shares progenitors, rna-seq
- GSE290816 Cell autonomous regional differences in oligodendrocyte precursor cell development and response to oncohistone H3.3 K27M [RNA-seq] 142 samples shares oligodendrocyte, rna-seq
- GSE282285 Aged muscle stem cells epigenetically drive the expansion of mesenchymal progenitors [bulk RNA-Seq] 31 samples shares progenitors, rna-seq
- GSE291075 The transcription factor NFIL3 drives innate lymphoid cell specification from lymphoid progenitors [RNA-seq - ex vivo, Nfil3] 27 samples shares progenitors, rna-seq
- GSE279386 Tp53 and Tet2 mutations cooperatively transform progenitors (RNA-Seq) 24 samples shares progenitors, rna-seq
- GSE293107 SKIDA1 transiently sustains MLL::ENL-Expressing hematopoietic progenitors during neonatal stages and promotes B-lineage priming [RNA-Seq] 24 samples shares progenitors, rna-seq
- GSE290817 Cell autonomous regional differences in oligodendrocyte precursor cell development and response to oncohistone H3.3 K27M [scRNA-seq] 22 samples shares oligodendrocyte, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.