IRAK4 is an immunological checkpoint in neuropsychiatric systemic lupus erythematosus
RNA-seq (gene expression) · mouse · 14 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- IRAK4 is an immunological checkpoint in neuropsychiatric systemic lupus erythematosusScientific reports · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE264121_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1101018 and SRA study SRP502125. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 14 more — browse all 14 samples with per-sample file links →
- GSE299922 A recombinant TACI-Fc fusion protein targets IgA plasma cells in a mouse model of systemic lupus erythematosus 58 samples shares erythematosus, systemic, lupus
- GSE218778 Extramedullary hematopoiesis and immune training drive systemic inflammation and associated organ damage in Systemic Lupus Erythematosus (RNA-seq) 12 samples shares erythematosus, systemic, lupus
- GSE330183 SLC7A11 deficiency exacerbates systemic lupus erythematosus by inducing instability and ferroptosis in regulatory T cells 9 samples shares erythematosus, systemic, lupus
- GSE275463 Immunomodulatory effects of microbiota-derived propionate in systemic lupus erythematosus 8 samples shares erythematosus, systemic, lupus
- GSE296556 Endogenous retroviruses promote aberrant T cell differentiation in systemic lupus erythematosus via the RIG-I pathway [mouse_CD4] 8 samples shares erythematosus, systemic, lupus
- GSE252782 DDIT3 deficiency ameliorates systemic lupus erythematosus by regulating B-cell activation and differentiation 6 samples shares erythematosus, systemic, lupus
- GSE276751 Gene expression profile at single cell level of lung from TRAF5 knockout mouse with Systemic Lupus Erythematosus-associated Pulmonary Arterial Hypertension (SLE-PAH) 2 samples shares erythematosus, systemic, lupus
- GSE218780 Extramedullary hematopoiesis and immune training drive systemic inflammation and associated organ damage in Systemic Lupus Erythematosus 22 samples shares erythematosus, systemic, lupus
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.