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Immunomodulatory effects of microbiota-derived propionate in systemic lupus erythematosus

GSE275463 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2024/09/30 Platform GPL34290
Summary
We performed RNAseq on total RNA extracted from kidney tissues from MRL-lpr micetreated with propionate and controls.We then performed differential expression analysis, meta-analysis, and gene set enrichment anaylsis using data obtained by RNA-seq of control and PA-treated mice.
Published in
Protective Role of Dietary Short-Chain Fatty Acid Propionate against Autoimmune Responses and Pathology of Systemic Lupus Erythematosus in MRL-lpr Mice
Wang H, Liang Y, Boor PJ et al. · The Journal of nutrition 2025 · PMID 40615087 · doi:10.1016/j.tjnut.2025.06.031
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Also filed as BioProject PRJNA1150989 and SRA study SRP528083. Searching any of these in the dataset finder brings you back here.

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