GEO series
Endothelial Parkin safeguards coronary microcirculation in myocardial ischemia/reperfusion injury
GSE264207
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2026/04/12
GPL24247
Summary
Gaining a deeper insight into the signals and molecular mechanisms that govern the function of coronary endothelial cells after MI/R could pave the way for the discovery of new preventative and therapeutic approaches. The functional role of Parkin in coronary microvascular injury in response to MI/R is unclear. Here, we investigated the upstream regulators and downstream effectors of Parkin against MI/R damage and examined the underlying mechanisms.
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