Sequencing-Guided Design of Genetically Encoded Small RNAs Targeting CAG Repeats for Selective Inhibition of Mutant Huntingtin
Non-coding RNA profiling · human · 41 samples
- What it is
- Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
- Organism
- Homo sapiens (human)
- Samples
- 41 samples: 28 distinct titles, 7 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Sequencing-guided design of genetically encoded small RNAs targeting CAG repeats for selective inhibition of mutant huntingtinMolecular therapy. Nucleic acids · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE264444_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
Also filed as BioProject PRJNA1102415 and SRA study SRP502395. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 41 sample titles: 28 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7764705 Parasrampuria_Round 1 shMCHR-33 full mimic
- GSM7764706 Parasrampuria_Round 2 shMCHR-33 full mimic
- GSM7764707 Parasrampuria_Round 3 shMCHR-33 full mimic
- GSM7764708 Parasrampuria_Round 4 shMCHR-33 full mimic
- GSM7764709 Parasrampuria_shHD1-1
- GSM7764710 Parasrampuria_shHD1L-1
- GSM7764711 Parasrampuria_shHD1L-1a
- GSM7764712 Parasrampuria_shHD1L-1b
- GSM7764713 Parasrampuria_shHD1L-1c
- GSM7764714 Parasrampuria_shHD1L-1d
- GSM7764715 Parasrampuria_shHD-33part
- GSM7764716 Parasrampuria_shHD-33part 3'k
- GSM7764717 Parasrampuria_shHD-33full
- GSM7764718 Parasrampuria_shHD-33full-mimic
- GSM7764719 Parasrampuria_shHD-33full_nb
- GSM7764720 Parasrampuria_shHD-33full_UAC
- GSM7764721 Parasrampuria_shHD-33full_30lp
- GSM7764722 Parasrampuria_shHD-33full_30lp2
- GSM7764723 Parasrampuria_shHD2.4
- GSM7764724 Parasrampuria_Round 1 NT
- GSM7764725 Parasrampuria_Round 2 NT
- GSM7764726 Parasrampuria_Round 3 NT
- GSM7764727 Parasrampuria_Round 4 NT
- GSM8214574 Parasrampuria_mRNA_Seq_mock_1
- GSM8214575 Parasrampuria_mRNA_Seq_mock_2
- GSM8214576 Parasrampuria_mRNA_Seq_mock_3
- GSM8214577 Parasrampuria_mRNA_Seq_shMCHR_1
- GSM8214578 Parasrampuria_mRNA_Seq_shMCHR_2
- GSM8214579 Parasrampuria_mRNA_Seq_shMCHR_3
- GSM8214580 Parasrampuria_mRNA_Seq_shHD2.4_1
- GSM8214581 Parasrampuria_mRNA_Seq_shHD2.4_2
- GSM8214582 Parasrampuria_mRNA_Seq_shHD2.4_3
- GSM8214583 Parasrampuria_mRNA_Seq_shHD-33full-mimic_1
- GSM8214584 Parasrampuria_mRNA_Seq_shHD-33full-mimic_2
- GSM8214585 Parasrampuria_mRNA_Seq_shHD-33full-mimic_3
- GSM8214586 Parasrampuria_mRNA_Seq_shHD-33full_nb_1
- GSM8214587 Parasrampuria_mRNA_Seq_shHD-33full_nb_2
- GSM8214588 Parasrampuria_mRNA_Seq_shHD-33full_nb_3
- GSM8214589 Parasrampuria_mRNA_Seq_shHD-33full_UAC_1
- GSM8214590 Parasrampuria_mRNA_Seq_shHD-33full_UAC_2
+ 1 more — browse all 41 samples with per-sample file links →
- GSE319266 Identification of target genes and regulatory networks for bone mineral density GWAS loci through systematic targeting and inhibition [hFOB BMD STING-seq] 24 samples shares inhibition, targeting
- GSE285823 ATR inhibition synergizes with alkylating PI polyamide targeting MYCN by suppressing DNA repair in MYCN-amplified neuroblastoma 16 samples shares inhibition, targeting
- GSE303446 Beyond CD30 Targeting: Brentuximab Vedotin Triggers Immunogenic Cell Death and Antitumor Immunity in Mycosis Fungoides, Overcoming Resistance via BCL2 Inhibition 13 samples shares inhibition, targeting
- GSE310878 Molecular phenotyping of diverse human skeletal muscles with CAGE-Seq 228 samples shares cag
- GSE199913 KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage 231 samples shares inhibition
- GSE254732 Inhibition of PCSK9 with evolocumab modulates lipoproteins and monocyte activation in high-risk ASCVD subjects 215 samples shares inhibition
- GSE300177 Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia 194 samples shares inhibition
- GSE275078 In vitro drug screening of RAF/MEK/ERK Inhibitors in combination with Autophagy inhibition in the context of two PDA Cell Lines 136 samples shares inhibition
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.