Somatic muscle engineering faithfully recapitulates a molecular spectrum of high-risk sarcomas
DNA methylation · mouse · 195 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Mus musculus (mouse)
- Samples
- 195 samples: 23 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
- Paper
- Somatic gene delivery faithfully recapitulates a molecular spectrum of high-risk sarcomasNature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE265875_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA1104601 and SRA study SRP503800. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 138 samples.
How we read this: 23 replicated groups read from 195 sample titles; they account for 138 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8229039 ASP_TFE_neo_P53_1
- GSM8229040 ASP_TFE_P53_1 ASP_TFE_P53
- GSM8229041 ASP_TFE_P53_3 ASP_TFE_P53
- GSM8229042 ASP_TFE_P53_3_CL2D ASP_TFE_P53_3_CL2D
- GSM8229043 ASP_TFE_P53_4 ASP_TFE_P53
- GSM8229044 Kras Kras
- GSM8229045 Kras_Bcor_1 Kras_Bco
- GSM8229046 Kras_Bcor_2 Kras_Bco
- GSM8229047 Kras_Bcor_3 Kras_Bco
- GSM8229048 Kras_Bcor_4 Kras_Bco
- GSM8229049 Kras_p53_1 Kras_p53
- GSM8229050 Kras_p53_2 Kras_p53
- GSM8229051 Kras_p53_3 Kras_p53
- GSM8229052 Kras_p53_4 Kras_p53
- GSM8229053 Kras_p53_5 Kras_p53
- GSM8229054 Kras_p53_6 Kras_p53
- GSM8229055 Muscle_1 Muscle
- GSM8229056 Muscle_2 Muscle
- GSM8229057 Muscle_3 Muscle
- GSM8229058 Muscle_4 Muscle
- GSM8229059 Muscle_5 Muscle
- GSM8229060 Muscle_6 Muscle
- GSM8229061 Neo_Kras_p53_1 Neo_Kras_p53
- GSM8229062 Neo_Kras_p53_2 Neo_Kras_p53
- GSM8229063 Neo_Kras_p53_3 Neo_Kras_p53
- GSM8229064 Nf1_p53_1 Nf1_p53
- GSM8229065 Nf1_p53_2 Nf1_p53
- GSM8229066 Nf1_p53_3 Nf1_p53
- GSM8229067 Nf1_p53_4 Nf1_p53
- GSM8229068 Nf1_p53_5 Nf1_p53
- GSM8229069 Nf1_p53_5_CL2D
- GSM8229070 NTRK_p53_1 NTRK_p53
- GSM8229071 NTRK_p53_1_CL_2D
- GSM8229072 NTRK_p53_2 NTRK_p53
- GSM8229073 NTRK_p53_3 NTRK_p53
- GSM8229074 NTRK_p53_4 NTRK_p53
- GSM8229075 NTRK_p53_5 NTRK_p53
- GSM8229076 NTRK_p53_6 NTRK_p53
- GSM8229077 NTRK_p53_neo_1 NTRK_p53_neo
- GSM8229078 NTRK_p53_neo_2 NTRK_p53_neo
+ 155 more — browse all 195 samples with per-sample file links →
- GSE265782 Somatic muscle engineering faithfully recapitulates a molecular spectrum of high-risk sarcomas [RNA-Seq] 81 samples shares recapitulates, engineering, faithfully, high-risk, spectrum, sarcomas, somatic, muscle
- GSE294913 Engineering a superactivator of smooth muscle gene expression with the Myocardin condensate forming region [ChIP-seq] 15 samples shares engineering, muscle
- GSE294914 Engineering a superactivator of smooth muscle gene expression with the Myocardin condensate forming region [RNA-seq] 15 samples shares engineering, muscle
- GSE293440 Combining high-risk ADRD mutations across genetically distinct mice 290 samples shares high-risk
- GSE243517 Rational cell fate engineering through chromatin dynamics 95 samples shares engineering
- GSE306439 Synthetic engineering demonstrates that synergy among enhancers involves an increase in transcriptionally productive enhancer-gene contacts [ChIP-Seq] 72 samples shares engineering
- GSE243516 Rational cell fate engineering through chromatin dynamics [RNA-Seq] 46 samples shares engineering
- GSE313869 Impact of Fc engineering on the transcriptional profile of monocytes and interstitial macrophages in the lungs of Hu-FcgR Tg mice after MA30 infection 36 samples shares engineering
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.