Engineering a superactivator of smooth muscle gene expression with the Myocardin condensate forming region [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 15 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 15 samples: 15 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Engineering a serum response factor superactivator of smooth muscle gene expression with a condensate-forming domainProceedings of the National Academy of Sciences of the United States of America · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294913_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1252029 and SRA study SRP579416. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 15 sample titles: 15 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8929219 ChIP-GFP SRF
- GSM8929220 ChIP-GFP SRF-MYOCD-TAD
- GSM8929221 ChIP-GFP SRF-MYOCD-FWYtoA
- GSM8929222 ChIP-GFP MYOCD-FWYtoA
- GSM8929223 ChIP-GFP SRF-FUS
- GSM8929224 ChIP-H3K27ac SRF
- GSM8929225 ChIP-H3K27ac SRF-MYOCD-TAD
- GSM8929226 ChIP-H3K27ac SRF-MYOCD-FWYtoA
- GSM8929227 ChIP-H3K27ac MYOCD-FWYtoA
- GSM8929228 ChIP-H3K27ac SRF-FUS
- GSM8929229 ChIP-Input SRF
- GSM8929230 ChIP-Input SRF-MYOCD-TAD
- GSM8929231 ChIP-Input SRF-MYOCD-FWYtoA
- GSM8929232 ChIP-Input MYOCD-FWYtoA
- GSM8929233 ChIP-Input SRF-FUS
- GSE294914 Engineering a superactivator of smooth muscle gene expression with the Myocardin condensate forming region [RNA-seq] 15 samples shares superactivator, engineering, condensate, myocardin, forming, smooth, muscle
- GSE306439 Synthetic engineering demonstrates that synergy among enhancers involves an increase in transcriptionally productive enhancer-gene contacts [ChIP-Seq] 72 samples shares engineering, chip-seq
- GSE239468 Condensate-promoting ENL mutation induces tumorigenesis via chromatin remodeling [ChIP-seq and CUT&Tag] 46 samples shares condensate, chip-seq
- GSE299636 WDR5 Remodels NANOG Condensates to Drive Transcriptional Programs and Sustain Stem Cell Identity [ChIP-seq] 28 samples shares condensate, chip-seq
- GSE265875 Somatic muscle engineering faithfully recapitulates a molecular spectrum of high-risk sarcomas 195 samples shares engineering, muscle
- GSE265782 Somatic muscle engineering faithfully recapitulates a molecular spectrum of high-risk sarcomas [RNA-Seq] 81 samples shares engineering, muscle
- GSE243513 Rational cell fate engineering through chromatin dynamics [ATAC-Seq] 20 samples shares engineering
- GSE291104 Pcf11/Spt5 condensates stall RNA polymerase II to facilitate termination and piRNA-guided heterochromatin formation [CUT&Tag] 12 samples shares condensate
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.