Transcriptomes of BNST brain regions from mouse model of anxiety
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 5 × FC vs 5 × MC vs 5 × FS vs 5 × MSGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Integrative analysis identifies region- and sex-specific gene networks and Mef2c as a mediator of anxiety-like behaviorCell reports · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE266128_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1105934. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 4 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8241132 FC-1 FC
- GSM8241133 FC-2 FC
- GSM8241134 FC-3 FC
- GSM8241135 FC-4 FC
- GSM8241136 FC-5 FC
- GSM8241137 MC-1 MC
- GSM8241138 MC-2 MC
- GSM8241139 MC-3 MC
- GSM8241140 MC-4 MC
- GSM8241141 MC-5 MC
- GSM8241142 FS-1 FS
- GSM8241143 FS-2 FS
- GSM8241144 FS-3 FS
- GSM8241145 FS-4 FS
- GSM8241146 FS-5 FS
- GSM8241147 MS-1 MS
- GSM8241148 MS-2 MS
- GSM8241149 MS-3 MS
- GSM8241150 MS-4 MS
- GSM8241151 MS-5 MS
- GSE254448 Transcriptomes across seven brain regions from mouse model of anxiety 10 samples shares transcriptomes, regions, anxiety, brain
- GSE98816 Single cell RNA-seq of mouse brain vascular transcriptomes 3186 samples shares transcriptomes, brain
- GSE299704 Meta-analysis of the brain transcriptomes of multiple genetic mouse models of schizophrenia highlights dysregulation in striatum and thalamus 235 samples shares transcriptomes, brain
- GSE99058 Single cell RNA-seq of mouse brain astrocyte transcriptomes 250 samples shares transcriptomes, brain
- GSE310518 bacTRAP profiling of astrocytes in five mouse brain regions in wildtype controls and hippocampus region in a Alzheimer's disease mouse model 30 samples shares regions, brain
- GSE332798 Transcriptomic profiling of morphine and LPS exposure across mouse brain regions 208 samples shares regions, brain
- GSE72826 Gene expression profiling of cell subpopulations from different regions of the mouse brain 36 samples shares regions, brain
- GSE330309 Impact of Sex Chromosomes and Gonad Type in Stress Susceptibility in Corticostriatal Brain Regions 96 samples shares regions, brain
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.