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AMH protects the ovary from doxorubicin by regulating cell fate and the response to DNA damage

GSE266600 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/05/24 Platform GPL24247
Summary
we aim to explore the single-cell mechanisms behind ovarian damage in prepubertal mice following doxorubicin (DOX) treatment, and how Anti-Müllerian hormone (AMH) prevents chemotherapy-induced pathological damage, using single-cell RNA sequencing as well as quantitative and morphometric histological evaluation.
Published in
AMH protects the ovary from doxorubicin by regulating cell fate and the response to DNA damage
Nguyen NMP, Chang EM, Chauvin M et al. · Proceedings of the National Academy of Sciences of the United States of America 2025 · PMID 39874288 · doi:10.1073/pnas.2414734122
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Also filed as BioProject PRJNA1107821 and SRA study SRP505711. Searching any of these in the dataset finder brings you back here.

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