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The gene expression profiles of HUVEC cells treated with LIMCH-overexpressed JAR cells-derived small extracellular vesicles.

GSE266603 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/11/25 Platform GPL24676
Summary
Preeclampsia is a major pregnancy complication leading to maternal and neonatal mortality, but the detailed pathogenesis remains unelucidated. Extracellular vesicles (EVs) contain proteins and nucleic acids inside and are responsible for intercellular communication. In this study, we investigated the roles of LIMCH1-containing EVs on vascular endothelial cells in vitro.
Published in
LIMCH1-enriched extracellular vesicles promote vascular permeability in early-onset preeclampsia
Matsuo S, Yokoi A, Ushida T et al. · Science advances 2026 · PMID 41604492 · doi:10.1126/sciadv.aeb8806
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Also filed as BioProject PRJNA1107927 and SRA study SRP505735. Searching any of these in the dataset finder brings you back here.

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