Early-life ketone body signaling promotes beige fat biogenesis through changes in histone acetylome and β-hydroxybutyrylome [bulk RNA-seq]
Single-cell RNA-seq · mouse · 14 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart. Read from the summary: GEO's own type field only says 'expression profiling by sequencing', so confirm it in the paper.
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Early-life ketone body signalling promotes beige fat biogenesis through changes in histone acetylome and β-hydroxybutyrylomeNature metabolism · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE267314_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1111050 and SRA study SRP507333. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 14 more — browse all 14 samples with per-sample file links →
- GSE268811 Early-life ketone body signaling promotes beige fat biogenesis through changes in histone acetylome and β-hydroxybutyrylome [scRNA-seq] 1 samples shares hydroxybutyrylome, early-life, biogenesis, acetylome, promotes, changes, histone, rna-seq
- GSE267320 Early-life ketone body signaling promotes beige fat biogenesis through changes in histone acetylome and β-hydroxybutyrylome [ChIP-seq] 20 samples shares hydroxybutyrylome, early-life, biogenesis, acetylome, promotes, changes, histone
- GSE242272 Prostaglandin E2-EP4 signaling shapes immunosuppressive tumor microenvironment in human tumors by suppressing bioenergetics and ribosome biogenesis in infiltrating immune cells [RNA-seq] 18 samples shares biogenesis, rna-seq
- GSE288334 Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions. [RNA-Seq] 18 samples shares early-life, rna-seq
- GSE277835 TUT1 and USB1, the biogenesis enzymes for 2′,3′-cyclic phosphate modification at U6 snRNA 3’ end, have distinct roles in mammalian development [RNA-seq] 17 samples shares biogenesis, rna-seq
- GSE282428 SMIM20 promotes complex IV biogenesis and Ca2+ Signalling in mice heart 8 samples shares biogenesis, promotes
- GSE235798 Atf4 promotes erythroid differentiation by regulating ribosome biogenesis via RPS19BP1 6 samples shares biogenesis, promotes
- GSE304247 FTO-Mediated m6A Demethylation Regulates PGC-1α-Dependent Mitochondrial Biogenesis to Attenuate Aluminum-Induced Neuronal Senescence [RNA-Seq] 6 samples shares biogenesis, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.