Dual targeting of processive transcription for Myc-driven circuitry in medulloblastoma
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 38 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Topic
- MedulloblastomaThis series is part of our curated briefing on it.
- Samples
- 38 samples: 37 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE267473_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1111545 and SRA study SRP507675. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 38 sample titles: 37 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8267104 D458 cells, Atuveciclib, 72 hours, replicate 1, RNAseq
- GSM8267105 D458 cells, Atuveciclib, 72 hours, replicate 2, RNAseq
- GSM8267106 D458 cells, Atuveciclib, 72 hours, replicate 3, RNAseq
- GSM8267107 D458 cells, DMSO, 72 hours, replicate 1, RNAseq
- GSM8267108 D458 cells, DMSO, 72 hours, replicate 2, RNAseq
- GSM8267109 D458 cells, DMSO, 72 hours, replicate 3, RNAseq
- GSM8267110 D425 cells, Atuveciclib, 72 hours, replicate 1, RNAseq
- GSM8267111 D425 cells, Atuveciclib, 72 hours, replicate 2, RNAseq
- GSM8267112 D425 cells, Atuveciclib, 72 hours, replicate 3, RNAseq
- GSM8267113 D425 cells, DMSO, 72 hours, replicate 1, RNAseq
- GSM8267114 D425 cells, DMSO, 72 hours, replicate 2, RNAseq
- GSM8267115 D425 cells, DMSO, 72 hours, replicate 3, RNAseq
- GSM8267116 D458 cells, TG02, 24 hours, replicate 1, RNAseq
- GSM8267117 D458 cells, TG02, 24 hours, replicate 2, RNAseq
- GSM8267118 D458 cells, TG02, 24 hours, replicate 3, RNAseq
- GSM8267119 D458 cells, DMSO, 24 hours, replicate 1, RNAseq
- GSM8267120 D458 cells, DMSO, 24 hours, replicate 2, RNAseq
- GSM8267121 D458 cells, DMSO, 24 hours, replicate 3, RNAseq
- GSM8267122 D425 cells, TG02, 24 hours, replicate 1, RNAseq
- GSM8267123 D425 cells, TG02, 24 hours, replicate 2, RNAseq
- GSM8267124 D425 cells, TG02, 24 hours, replicate 3, RNAseq
- GSM8267125 D425 cells, DMSO, 24 hours, replicate 1, RNAseq
- GSM8267126 D425 cells, DMSO, 24 hours, replicate 2, RNAseq
- GSM8267127 D425 cells, DMSO, 24 hours, replicate 3, RNAseq
- GSM8267128 D458 cells, IgG, DMSO, replicate 1, ChIP
- GSM8267129 D458 cells, IgG, DMSO, replicate 2, ChIP
- GSM8267130 D458 cells, Myc, DMSO, replicate 1, ChIP
- GSM8267131 D458 cells, Myc, DMSO, replicate 2, ChIP
- GSM8267132 D458 cells, IgG, TG02, replicate 1, ChIP
- GSM8267133 D458 cells, IgG, TG02, replicate 2, ChIP
- GSM8267134 D458 cells, Myc, TG02, replicate 1, ChIP
- GSM8267135 D458 cells, Myc, TG02, replicate 2, ChIP
- GSM8267136 D458 cells, H3K4me1, replicate 1, ChIP
- GSM8267137 D458 cells, H3K4me1, replicate 2, ChIP
- GSM8267138 D458 cells, IgG, replicate 1, ChIP
- GSM8267139 D458 cells, IgG, replicate 2, ChIP
- GSM8267140 Group 3 Medulloblastoma - UPN1355
- GSM8267141 Group 3 Medulloblastoma - UPN1433
- GSE267469 Dual targeting of processive transcription for Myc-driven circuitry in medulloblastoma [RNA-seq] 24 samples same disease briefing · shares medulloblastoma, transcription, processive, myc-driven, targeting, circuitry, dual
- GSE267470 Dual targeting of processive transcription for Myc-driven circuitry in medulloblastoma [CUT&RUN] 12 samples same disease briefing · shares medulloblastoma, transcription, processive, myc-driven, targeting, circuitry, dual
- GSE280973 Transcriptional Regulation of Protein Synthesis by Mediator Kinase Represents a Therapeutic Vulnerability in MYC-driven Medulloblastoma 20 samples same disease briefing · shares medulloblastoma, transcription, myc-driven
- GSE229150 The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma 30 samples same disease briefing · shares medulloblastoma, transcription
- GSE291915 The Hira complex regulates Gli3R-dependent transcription in Hedgehog signaling and medulloblastoma cell growth and migration [RNA-seq] 12 samples same disease briefing · shares medulloblastoma, transcription
- GSE37385 Subgroup specific somatic copy number aberrations in the medulloblastoma genome 1382 samples same disease briefing · shares medulloblastoma
- GSE270126 Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency. 219 samples same disease briefing · shares medulloblastoma
- GSE270125 Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency [CUT&Run] 169 samples same disease briefing · shares medulloblastoma
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.