Comprehensive serum metabolic snapshots enable diagnosis, prognosis, and monitoring for brainstem gliomas [I]
RNA-seq (gene expression) · human · 17 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 17 samples: 5 × U87MG-Luc cells, tumo vs 4 × U87MG-Luc cells, controlGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Serum metabolic profiling enables diagnosis, prognosis, and monitoring for brainstem gliomasNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE267692_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1112417 and SRA study SRP508194. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 8 samples read as cases, 4 as controls.
How we read this: 2 replicated groups read from 17 sample titles; they account for 9 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8273208 U87MG-Luc cells, tumor1 U87MG-Luc cells, tumo
- GSM8273209 U87MG-Luc cells, tumor2 U87MG-Luc cells, tumo
- GSM8273210 U87MG-Luc cells, tumor3 U87MG-Luc cells, tumo
- GSM8273211 U87MG-Luc cells, tumor4 U87MG-Luc cells, tumo
- GSM8273212 U87MG-Luc cells, tumor5 U87MG-Luc cells, tumo
- GSM8273213 U87MG-Luc cells, control1 U87MG-Luc cells, control
- GSM8273214 U87MG-Luc cells, control2 U87MG-Luc cells, control
- GSM8273215 U87MG-Luc cells, control3 U87MG-Luc cells, control
- GSM8273216 U87MG-Luc cells, control4 U87MG-Luc cells, control
- GSM8273217 U87MG-Luc cells, tumor1, befor radiotherapy
- GSM8273218 U87MG-Luc cells, tumor2, befor radiotherapy
- GSM8273219 U87MG-Luc cells, tumor3, befor radiotherapy
- GSM8273220 U87MG-Luc cells, tumor4, befor radiotherapy
- GSM8273221 U87MG-Luc cells, tumor1, after radiotherapy
- GSM8273222 U87MG-Luc cells, tumor2, after radiotherapy
- GSM8273223 U87MG-Luc cells, tumor3, after radiotherapy
- GSM8273224 U87MG-Luc cells, tumor4, after radiotherapy
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.