Transgenerational inheritance of diabetes susceptibility in male offspring with maternal hyperandrogenism
RNA-seq (gene expression) · mouse · 11 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples: 6 × HA vs 5 × CtrlGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transgenerational inheritance of diabetes susceptibility in male offspring with maternal androgen exposureCell discovery · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE267720_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1112456 and SRA study SRP504965. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 11 samples.
How we read this: 2 replicated groups read from 11 sample titles; they account for 11 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8243863 Ctrl_1 Ctrl
- GSM8243864 Ctrl_2 Ctrl
- GSM8243865 Ctrl_3 Ctrl
- GSM8243866 HA_1 HA
- GSM8243867 HA_2 HA
- GSM8243868 HA_3 HA
- GSM8243869 HA_4 HA
- GSM8253991 Ctrl_1 Ctrl
- GSM8253992 Ctrl_2 Ctrl
- GSM8253993 HA_1 HA
- GSM8253994 HA_2 HA
- GSE266255 Transgenerational inheritance of diabetes susceptibility in male offspring with maternal hyperandrogenism [RNA-Seq] 7 samples shares transgenerational, hyperandrogenism, susceptibility, inheritance, offspring, diabetes, maternal, male
- GSE43239 Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals 16 samples shares transgenerational, susceptibility, inheritance, diabetes
- GSE43187 Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals (NimbleGen expression) 12 samples shares transgenerational, susceptibility, inheritance, diabetes
- GSE273675 Parental Alcohol Exposures Promote Increased Susceptibility to Hepatocellular Carcinoma in Adult Male Offspring 20 samples shares susceptibility, offspring, male
- GSE317156 Developmental control of DNA damage responses in α- and β-cells shapes the selective beta-cell susceptibility in diabetes 28 samples shares susceptibility, diabetes
- GSE315104 Developmental control of DNA damage responses in α- and β-cells shapes the selective beta-cell susceptibility in diabetes [RNA-Seq] 26 samples shares susceptibility, diabetes
- GSE280782 Preterm birth increases susceptibility to hyperglycemia-induced glomerular alterations in the kidneys of male mice 24 samples shares susceptibility, male
- GSE280781 Preterm birth increases susceptibility to hyperglycemia-induced glomerular alterations in the kidneys of male mice [bulk RNA-seq] 20 samples shares susceptibility, male
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.