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Single-cell transcriptomics reveals a pivotal role of DOCK2 in Sjögren’s disease

GSE268532 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2024/12/19 Platform GPL24247
Summary
Sjögren's disease (SjD) is an autoimmune condition characterized by the dysfunction of the salivary and lacrimal glands. The study aimed to decipher the pathogenic cell populations and their immunological pathways in the salivary glands. We further determined the therapeutic effect of inhibiting DOCK2 shared by novel clusters of CD8Cd8+ T cells in a SjD mouse model.
Published in
Single-Cell Transcriptomics Reveals a Pivotal Role of DOCK2 in Sjögren Disease
Shen Y, Voigt A, Bhattacharyya I et al. · ACR open rheumatology 2024 · PMID 39382155 · doi:10.1002/acr2.11738
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Also filed as BioProject PRJNA1117745 and SRA study SRP510419. Searching any of these in the dataset finder brings you back here.

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