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Gene expression profile at single cell level of kidney from Sglt2 WT and mutant mice fed with normal diet and high-fat diet.

GSE268593 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/07/09 Platform GPL21103
Summary
Analysis of scRNA seq data showed emergence of a new cluster of proximal tubular cells with a distinct molecular fingerprint, predominantly found in WT-HFD mice.
Published in
SGLT2 inhibition protects kidney function by SAM-dependent epigenetic repression of inflammatory genes under metabolic stress
Maekawa H, Zhou Y, Aoi Y et al. · The Journal of clinical investigation 2025 · PMID 41031893 · doi:10.1172/JCI188933
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Also filed as BioProject PRJNA1117868 and SRA study SRP510591. Searching any of these in the dataset finder brings you back here.

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