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Sub-chronic administration of AM6545 enhances cognitive performance and induces hippocampal synaptic plasticity changes in naïve mice

GSE268761 Mus musculus Expression profiling by high throughput sequencing 7 samples Submitted 2025/01/30 Platform GPL24247
Summary
Using RNA sequencing, we perform gene expression profile of three female mice treated with vehicle and four female mice sub-chronically treated with AM6545 at a dose of 1 mg/kg. To evaluate hippocampal modifications promoted by peripheral CB1R modulation, we analyze at transcript level hippocampal synaptoneurosomes fractions.
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Sub-chronic administration of AM6545 enhances cognitive performance and induces hippocampal synaptic plasticity changes in naïve mice
Bergadà-Martínez A, de Los Reyes-Ramírez L, Martínez-Torres S et al. · British journal of pharmacology 2025 · PMID 40102206 · doi:10.1111/bph.70015
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Also filed as BioProject PRJNA1118698 and SRA study SRP511003. Searching any of these in the dataset finder brings you back here.

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